Lipid Profile and Serum Leptin

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Insulin, C-Peptide and HOMA-IR Mean fasting insulin concentrations were significantly higher in offspring of BDP as compared to those of NDP but no statistically significant difference in mean insulin concentration was found between NDP and ODP groups. The insulin resistance as assessed by HOMA-IR was markedly higher in the ODP and BDP group as compared to the control group (Tables 2 and 3). The mean serum C-peptide levels in offspring of diabetic parents (ODP and BDP groups) were also significantly greater (P=0.026 and P<0.001, respectively) than in the control group (Tables 2 and 3). Fasting C-peptide concentrations were higher than 630 pmol/ml in 18% of offspring of NDP, 47% of ODP and 55% of BDP.

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تاریخ انتشار 2008